Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophrenia Patients

Not Applicable

• Conditions: Dyskinesias; Psychosis; Parkinsonism; Schizophrenia
• Interventions: Behavioral: RAS for at-risk individuals; Behavioral: No RAS for schizophrenia patients; Behavioral: No RAS for at-risk individuals; Behavioral: Rhythmic auditory stimulation (RAS) for schizophrenia patients

• Registration Number: NCT04553835
• Lead Sponsor: Dr WANG Shumei

Brief Summary

The purpose of this research is to examine effects of movement training with the aid of rhythmic auditory stimulation (RAS) on reducing severity of dyskinesia and bradykinesia in at-risk individuals and schizophrenia patients. The investigators hypothesize that training with the aid of RAS reduced severity of bradykinesia and dyskinesia in at-risk individuals as well as in schizophrenia patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-31
• Study First Submitted: 2020-09-12
• Study First Submitted QC: 2020-09-16
• Study First Posted: 2020-09-17
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-20
• Last Update Posted: 2022-05-23
• Primary Completion: 2022-12-31
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
at risk- RAS	RAS for at-risk individuals	At-risk individuals in the experimental group will undergo upper-limb movement training with the aid of RAS.
schizophrenia- no RAS	No RAS for schizophrenia patients	Schizophrenia patients in the control group will receive upper-limb training without the aid of RAS.
at risk- no RAS	No RAS for at-risk individuals	At-risk individuals in the control group will receive upper-limb training without the aid of RAS.
schizophrenia- RAS	Rhythmic auditory stimulation (RAS) for schizophrenia patients	Schizophrenia patients in the experimental group will undergo upper-limb movement training with the aid of rhythmic auditory stimulation (RAS).

Primary Outcome Measures

Name	Time	Method
Motion analysis by using an eight-camera motion capture system (VICON; Oxford Metrics Group, Oxford, UK)	Within one week right after the last session of the intervention	normalized number of movement units (representing severity of dyskinesia). Unit: units/mm

Trial Locations

Locations (1)

Hong Kong Polytechnic University; 🇭🇰 Kowloon, Hong Kong