ISRCTN16889608已完成未知

Influence of genetic and epigenetic factors on susceptibility to retinopathy of prematurity and its progression

Institute of Environmental Health (ISAMB) of the Lisbon School of Medicine0 个研究点目标入组 900 人开始时间: 2022年6月22日最近更新: 2023年6月20日

适应症

试验速览

2023 Results article in https://doi.org/10.1007/s00417-023-06072-7 (added 09/06/2023)

•Preterm infants and their mothers, with at least one of the following newborn characteristics:
•1. Born before 32 weeks of gestational age
•2. Born with a birth weight of less than 1500 g

•1. Infants:
•1.1. The existence of major congenital malformations
•1.2. Ophthalmological pathologies, congenital or acquired (during the first 12 weeks of life) not related to ROP with the exception of conjunctivitis, keratitis and congenital obstruction of the tear-nasal canal
•2. Mothers:
•2.1. Diabetes
•2.2. Gestation resulting from artificial fertilization
•2.3. Insufficient clinical data
•3. Legal guardians:
•3.1. Absence of informed consent
•It should be noted that when the mother is excluded, the infant can still form part of the study, provided informed consent is given.

发起方

Institute of Environmental Health (ISAMB) of the Lisbon School of Medicine