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VALIDATE Pump-priming project

Not Applicable
Conditions
Health Condition 1: B998- Other infectious diseaseHealth Condition 2: A150- Tuberculosis of lung
Registration Number
CTRI/2020/06/025539
Lead Sponsor
VALIDATE PumpPriming Grant Medical Research Council MRC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients diagnosed with culture /PCR confirmed melioidosis.

Patients diagnosed with tuberculosis confirmed by smear positive and/or Gene Xpert.

Age and Gender matched healthy controls with and without diabetes mellitus

Exclusion Criteria

Patients below 18 years of age

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. To determine the antigen specific cellular response during TB and melioidosis in Indian subjects <br/ ><br>2. To determine the differences in the cellular metabolism of TB and melioidosis patients with and without diabetes mellitusTimepoint: 1 Year
Secondary Outcome Measures
NameTimeMethod
To know the role of difference in cellular metabolism of diabetes mellitus leading to increased susceptibility to TB and melioidosis.Timepoint: 1 year
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