Long-stayer Critically Ill Patients: is the Metabolic and Nutritional Therapy in the ICU Creating the Problem?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 205
- 试验地点
- 1
- 主要终点
- Vital Status
研究概览
简要总结
The intensive care (ICU) patient population has increasing number of very long ICU stays. Long-stayers are usually defined as requiring more than 1 week of mechanical ventilation and of ICU therapy: little is know about their metabolic characteristics and their relation to outcome. The study aims at describing the demographic, nutritional and metabolic aspects of their stay.
Analysis of 200-250 consecutive patients admitted to the ICU long-stayer program.
详细描述
Data extracted from the computerized ICU system (PDMS): age, Simplified acute physiology score (SAPSII), weight, BMI, Nutrition Risk Score (NRS-2002), daily energy, protein, and glucose intakes, Energy balance, blood glucose (dysglycemia and Glu variability) and lactate, 24hr-insulin (Goal Glu 6-8 mmol/l).
Outcome variables: length of stay (LICU), muscle strength (MRC), vital status at 90 days.
Patients will be followed in detail until ICU discharge and for vital status until day 90 after admission Data will be presented as mean or median, univariate and multivariate analysis will be performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ICU length of stay > 7 days and enrollment to the long-stayer ICU program
排除标准
- •Major burns
- •Brain injury
- •Severe neurological condition as primary disease
结局指标
主要结局
Vital Status
时间窗: up to 90 days
Alive or dead at 90 days after ICU admission
次要结局
- Force(up to 90 days)
研究者
Mette M Berger
Clinical Professor
Centre Hospitalier Universitaire Vaudois