Metabolic and Nutritional Characteristics of Long-stayer ICU Patients
- Conditions
- Critically Ill
- Registration Number
- NCT03938961
- Lead Sponsor
- Centre Hospitalier Universitaire Vaudois
- Brief Summary
The intensive care (ICU) patient population has increasing number of very long ICU stays. Long-stayers are usually defined as requiring more than 1 week of mechanical ventilation and of ICU therapy: little is know about their metabolic characteristics and their relation to outcome. The study aims at describing the demographic, nutritional and metabolic aspects of their stay.
Analysis of 200-250 consecutive patients admitted to the ICU long-stayer program.
- Detailed Description
Data extracted from the computerized ICU system (PDMS): age, Simplified acute physiology score (SAPSII), weight, BMI, Nutrition Risk Score (NRS-2002), daily energy, protein, and glucose intakes, Energy balance, blood glucose (dysglycemia and Glu variability) and lactate, 24hr-insulin (Goal Glu 6-8 mmol/l).
Outcome variables: length of stay (LICU), muscle strength (MRC), vital status at 90 days.
Patients will be followed in detail until ICU discharge and for vital status until day 90 after admission Data will be presented as mean or median, univariate and multivariate analysis will be performed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 205
- ICU length of stay > 7 days and enrollment to the long-stayer ICU program
- Major burns
- Brain injury
- Severe neurological condition as primary disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vital Status up to 90 days Alive or dead at 90 days after ICU admission
- Secondary Outcome Measures
Name Time Method Force up to 90 days Muscle strength measured by Medical research Council (MRC) score
Trial Locations
- Locations (1)
Adult ICU and Burns, University of Lausanne Hospital
🇨ðŸ‡Lausanne, Vaud, Switzerland