Methods of Weight Loss in Overweight Coronary Patients
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Fat Mass
研究概览
简要总结
We hypothesize that a combination of high-caloric expenditure exercise and behavioral weight loss counseling would lead to a greater loss of fat mass and a greater improvement in cardiometabolic risk factors that standard (lower caloric expenditure) cardiac rehabilitation exercise plus counseling.
详细描述
We hypothesize that a combination of high-caloric expenditure exercise and behavioral weight loss counseling would lead to a greater loss of fat mass and a greater improvement in cardiometabolic risk factors that standard (lower caloric expenditure) cardiac rehabilitation exercise plus counseling.
The study population consists of overweight (BMI >27) patients with established coronary heart disease. The exercise and counseling program was of 4 months duration with extended follow up at 1 year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 21 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Coronary heart disease
- •BMI > 27
- •Peak Vo2 > 14.4 ml/kg/min
排除标准
- •Presence of diabetes
研究组 & 干预措施
1
Arm 1: high caloric expenditure exercise plus dietary counseling
干预措施: high caloric expenditure exercise (Behavioral)
2
Arm 2: low caloric expenditure exercise plus dietary counseling
干预措施: low caloric expenditure exercise plus dietary counseling (Behavioral)
结局指标
主要结局
Fat Mass
时间窗: 4 months, 12 months
次要结局
- Intrabdominal (visceral) fat(4 months)
- Insulin stimulated glucose disposal(4 months)