14C-acetaminophen microdose clinical trial using AMS

Not Applicable

• Conditions: healthy volunteer

• Registration Number: JPRN-UMIN000002084
• Lead Sponsor: APDD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-21
• Study Completion: 2009-08-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

Not provided

Exclusion Criteria

the investigors must ensure that all subjects being considerd meet the following exclusion criteria or conditions 1)peptic ulcer 2)dysemia 3)kidney stone 4)history of cardiac disease 5)imparment of liver or kidney functions 6)any medical condition that reqires medical attention 7) recent (past 4 months) participation in other clinical trial and the investigator determines this trial participation inadequate 8)history of allergy to acetaminophen and probenecid 9)history of aspirin indeced asthma 10)donation of 400mL or more of blood within 3 months prior to participation, donation of 200mL or more of blood within 1 month prior to participation, or donation of component blood within 2 weeks prior to participation 11)positive serologic reaction of syphilis, positive result of HIV test, HBsAg and HCVAb 12)history of multiple and recurring allergies to medicines or food 13)history of drug or alcoholabuse 14) the investigator determines this trial participation inadequate

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
detection from radioactive concentraions of plasma, urin and feces samples.