临床试验/NCT07709247

NCT07709247尚未招募不适用

Osteoporoz Hastalarında Tükürük Sitokin, Matrix Metalloproteinase 8 ve Diş Çürüğünün Değerlendirilmesi

Afyonkarahisar Health Sciences University0 个研究点目标入组 50 人开始时间: 2026年7月10日最近更新: 2026年7月16日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 50
主要终点: Salivary Cytokine Levels

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Cross Sectional

入排标准

年龄范围: 45 Years 至 75 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia

排除标准

•Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months

结局指标

主要结局

Salivary Cytokine Levels

时间窗: day 1

Measurement of cytokine levels in saliva samples collected from osteoporosis patients

次要结局

未报告次要终点

研究者

发起方

Afyonkarahisar Health Sciences University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Kübra Karaçam

Assistant Professor

Afyonkarahisar Health Sciences University

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