Ibuprofen-Coated Absorbable Suture for Post-Operative Pain Management in Periodontal Surgical Procedures: A Single-Blind Randomized Controlled Trial
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
This study aims to evaluate the effectiveness of ibuprofen coated absorbable sutures in reducing postoperative pain after functional crown lengthening procedures. Postoperative pain following periodontal surgery is common and is usually managed with systemic non steroidal anti inflammatory drugs. However prolonged systemic use may lead to adverse effects and reduced drug availability at the surgical site. Local drug delivery through analgesic coated sutures may provide targeted pain relief while minimizing systemic complications.
The study is designed as a single blind randomized controlled clinical trial including 34 systemically healthy patients aged 15 to 65 years who require functional crown lengthening with an undisplaced flap. Participants will be randomly allocated into two groups. The test group will receive ibuprofen coated polyglactin 910 absorbable sutures, while the control group will receive non coated polyglactin 910 absorbable sutures. Pain will be assessed using a visual analogue scale at 2 hours 6 hours 24 hours and 48 hours after surgery. Healing will be evaluated using a healing index on the third and seventh postoperative days.
The primary objective is to determine whether ibuprofen coated sutures significantly reduce postoperative pain compared to conventional sutures. The secondary objective is to evaluate their effect on wound healing. The study hypothesizes that analgesic coated sutures will reduce postoperative pain without adversely affecting healing. The findings may contribute to improved localized pain management strategies in periodontal surgical procedures while reducing reliance on systemic analgesics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients who are clinically, radiographically and after through laboratory investigations are eligible for functional crown lengthening procedure with undisplaced flap involving 1 or 2 teeth
- •No existing Oro-facial pain.
- •Patient with age group of 15 to 65 years.
- •Systemically healthy patient.
- •No need for antimicrobial prophylaxis.
排除标准
- •Patients who have taken analgesic 7 days or less prior to beginning the study.
- •Patient who is a known case of allergy/ intolerance to ibuprofen.
- •Habit of tobacco consumption in any form.
- •Pregnant and lactating women.
- •Patients who refuse to provide written informed consent.
研究者
Dr Rashi Jhanwar
Tatyasaheb Kore Dental College and Research Centre, Nave Pargaon
