NCT00089856终止3 期
A Phase III Randomized, Open-Label Study of CG1940 and CG8711 Versus Docetaxel and Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer Who Are Chemotherapy-Naïve
Cell Genesys125 个研究点 分布在 1 个国家目标入组 626 人开始时间: 2004年7月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 发起方
- 入组人数
- 626
- 试验地点
- 125
- 主要终点
- Survival
研究概览
简要总结
The purpose of this study is to compare the duration of survival between GVAX® immunotherapy for prostate cancer and chemotherapy treatment in patients with prostate cancer who no longer respond to hormone therapy, who have documented metastases, and who have not been treated with chemotherapy in the past.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of or clinical history consistent with adenocarcinoma of the prostate
- •Metastatic prostate cancer deemed to be unresponsive or refractory to hormone therapy
- •Detectable metastases
- •Any Gleason score
- •ECOG performance status 0-2
排除标准
- •Prior treatment with chemotherapy
- •Prior Immunotherapy
- •Prior treatment with gene therapy
- •Significant cancer related pain
研究组 & 干预措施
2
Other
Standard of care - chemotherapy
干预措施: Chemotherapy (Taxotere and prednisone) (Drug)
1
Experimental
Immunotherapy
干预措施: Immunotherapy with allogeneic prostate vaccine (Biological)
结局指标
主要结局
Survival
时间窗: 0
次要结局
- Bone pain and bone related events(0)
研究者
研究点 (125)
Loading locations...
相似试验
已完成
2 期
Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)Vulvar High Grade Squamous Intraepithelial Lesion (HSIL)Vulvar DysplasiaVulvar Intraepithelial Neoplasia (VIN)VIN2VIN3Pre-cancerous Lesions of the VulvaHuman Papillomavirus (HPV)NCT03180684Inovio Pharmaceuticals33
撤回
2 期
A Phase II Clinical Trial of Chemo-radiotherapy in Combination With INO-3112 in Patients With Locally Advanced Cervical CancerUterine Cervical NeoplasmsNCT02501278European Organisation for Research and Treatment of Cancer - EORTC
已完成
3 期
A Trial of Grazax in Subjects With HayfeverAllergyNCT00421655ALK-Abelló A/S329
已完成
3 期
Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib AloneHepatocellular Carcinoma (HCC)NCT02562755SillaJen, Inc.459
Unknown
3 期
Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract CarcinomaBiliary Tract (Intrahepatic, Extrahepatic Cholangiocarcinoma, Gall Bladder) CancerNCT01470443Samsung Medical Center240