High Intensity Interval Exercise Versus Focused Ultrasound on Insulin Resistance in Diabetic Female Patients With Abdominal Obesity
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 主要终点
- Body mass index
研究概览
简要总结
Obesity and diabetes share a common insulin resistance pathway and contribute to chronic hyperglycemia. Both high-intensity interval exercise (HIIE) and focused ultrasound (FUS) have been explored in the context of managing insulin resistance in diabetic individuals with abdominal obesity, though they operate through different mechanisms and have different implications.
详细描述
Forty diabetic females aged 25 to 35 years old and body mass index was ≥ 30 kg/m², will participate in this study. They will be assigned into two equal groups, Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet. Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet. Assessment of abdominal obesity will be applied pre and post treatment through measuring Body mass index (BMI), Waist circumference (WC) in addition to Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •They will be recruited from El_shinnawy physical therapy Centre.
- •All are suffering from abdominal obesity
- •Their age between 25-35 years old
- •Their body mass index more than 30 kg/m2,
- •Their waist circumference ranged from 88 cm
- •The fat thickness at the treatment area was at least 2.5 cm
排除标准
- •Females having any skin diseases in the abdomen.
- •Female suffering from any physical or mental disorders.
- •Females suffering from abdominal scars or hernia
- •Females didn´t take any medication that might affect their weight all over the study period.
- •Females complaining from any cardiovascular disorders.
结局指标
主要结局
Body mass index
时间窗: Before starting the study and after 4 months of treatment
The weight and height of each woman in both groups will be measured to calculate the body mass index (BMI)
Value of HbA1c and HOMA-IR hormone
时间窗: Before starting the study and after 4 months of treatment
Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance.
Waist circumference
时间窗: Before starting the study and after 4 months of treatment
Assessment of waist circumference of each woman by the tape measurement
Skin fold
时间窗: Before starting the study and after 4 months of treatment
The thickness of the abdominal fold will be measured using skinfold calipers to provide information on changes in subcutaneous fat in the abdominal region.
次要结局
未报告次要终点
研究者
Noha Ahmed Fouad Abd-Elrahman
Departments of physical therapy for women's health, Faculty of Physical Therapy, Badr University in Cairo.
Badr University