Relationship of metabolic syndrome withcognitive functioning in persons with Severe Mental Illness
- Conditions
- Health Condition 1: F30-F39- Mood [affective] disordersHealth Condition 2: F20-F29- Schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders
- Registration Number
- CTRI/2022/01/039675
- Lead Sponsor
- Government Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Persons with Severe Mental Illness. Any gender. Aged between 18 and 50 years. Has adequate capacity (as per section 4 of Mental Health Care Act, 2017) to give consent.
Those uncooperative for assessment of metabolic syndrome and neuro-cognitive testing. Those with history of delay in developmental milestones. Those with medically diagnosable and /or self-reported and / or history of: Auditory impairment, Visual impairment(except those by uncorrected refractive errors) colour blindness. Those with co-morbid conditions like: Organic brain syndrome, Head injury,Past history of cerebrovascular accident,Epilepsy, Diagnosed medical conditions like (hypothyroidism, chronic kidney disease, heart failure and end stage carcinoma patients) and history of CABG. Those with active suicidal tendencies. Those with co-morbid substance dependence except nicotine and caffeine. Patients receiving Cognitive Enhancement Therapy, or Cognitive Behaviour Therapy in last
6 weeks. Patients receiving Electro Convulsive Therapy (ECT) in last 6 weeks
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In accordance with previous studies, neurocognitive functioning in persons with severe mental illness and metabolic syndrome shall have deficits or deficits of higher percentiles when compared with persons having severe mental illness without metabolic syndrome.Timepoint: Baseline data will be collected.
- Secondary Outcome Measures
Name Time Method Prevalence of metabolic syndrome in persons with Severe Mental Illness.Timepoint: Baseline.;The results can be used to strategize preventive measures against metabolic syndrome and plan cognitive enhancement therapies in persons with Severe Mental Illness, in addition to the treatment they are receiving. In persons with Severe Mental Illness, along with usual treatment, focus can be <br/ ><br>given to preventive interventions too, in relation to the metabolic syndrome as well as cognitive deficits (like cognitive enhancement therapy).Timepoint: Not applicable.