MedPath

Docetaxel in Treating Patients With Recurrent or Persistent Endometrial Carcinoma (Cancer)

Phase 2
Completed
Conditions
Endometrial Cancer
Registration Number
NCT00085332
Lead Sponsor
Gynecologic Oncology Group
Brief Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die.

PURPOSE: This phase II trial is studying how well docetaxel works in treating patients with recurrent or persistent endometrial carcinoma (cancer).

Detailed Description

OBJECTIVES:

* Determine the antitumor activity of docetaxel in patients with recurrent or persistent endometrial carcinoma.

* Determine the toxicity of this drug in these patients.

OUTLINE: This is a multicenter study.

Patients receive docetaxel IV over 1 hour on days 1, 8, and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

Patients are followed every 3 months for 2 years and then every 6 months for 3 years.

PROJECTED ACCRUAL: A total of 19-51 patients will be accrued for this study within 10-18 months.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (75)

Comprehensive Cancer Center at University of Alabama at Birmingham

🇺🇸

Birmingham, Alabama, United States

CCOP - Western Regional, Arizona

🇺🇸

Phoenix, Arizona, United States

Jonsson Comprehensive Cancer Center at UCLA

🇺🇸

Los Angeles, California, United States

Women's Cancer Center - Los Gatos

🇺🇸

Los Gatos, California, United States

Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center

🇺🇸

Orange, California, United States

University of Colorado Cancer Center at University of Colorado Health Sciences Center

🇺🇸

Denver, Colorado, United States

Yale Comprehensive Cancer Center

🇺🇸

New Haven, Connecticut, United States

CCOP - Christiana Care Health Services

🇺🇸

Newark, Delaware, United States

Walter Reed Army Medical Center

🇺🇸

Washington, District of Columbia, United States

H. Lee Moffitt Cancer Center and Research Institute at University of South Florida

🇺🇸

Tampa, Florida, United States

Scroll for more (65 remaining)
Comprehensive Cancer Center at University of Alabama at Birmingham
🇺🇸Birmingham, Alabama, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.