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临床试验/NCT05980442
NCT05980442
招募中
不适用

Randomized, Controlled, Single Center Observational Study to Compare the Safety and Performance of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty

Aesculap AG2 个研究点 分布在 1 个国家目标入组 140 人2024年7月3日

概览

阶段
不适用
干预措施
Navigated total knee arthroplasty
疾病 / 适应症
Osteoarthritis, Knee
发起方
Aesculap AG
入组人数
140
试验地点
2
主要终点
Functional outcome of the Knee Surgery measured by the Knee Society Score (KSS) (functional component)
状态
招募中
最后更新
上个月

概览

简要总结

Randomized, controlled, single center observational study to compare the safety and performance of navigation-assisted OrthoPilot Elite and robotic-assisted MAKO total knee arthroplasty (TKA). The aim of the study is the comparison of the clinical outcome between navigated and robotic-assisted TKA. The hypothesis of the study is that both treatments achieve similar results regarding functional and clinical aspects.

注册库
clinicaltrials.gov
开始日期
2024年7月3日
结束日期
2028年12月1日
最后更新
上个月
研究类型
Observational
性别
All

研究者

发起方
Aesculap AG
责任方
Sponsor

入排标准

入选标准

  • Indication for a TKA with a fixed-bearing total knee endoprosthesis
  • Written informed consent for participating in the clinical study

排除标准

  • Patient age \<18 years and \>90 years
  • Patient not willing to participate at the follow-up
  • Pregnancy
  • retropatellar arthrosis requiring patella resurfacing
  • American Society of Anaesthesiologists (ASA) Classification \>3

研究组 & 干预措施

OrthoPilot® Elite

navigated / computer assisted total knee replacement surgery

干预措施: Navigated total knee arthroplasty

MAKO

robot assisted total knee replacement surgery

干预措施: Robot assisted total knee arthroplasty

结局指标

主要结局

Functional outcome of the Knee Surgery measured by the Knee Society Score (KSS) (functional component)

时间窗: one year postoperatively

Functional result one year postoperatively measured with the functional component of the Knee Society Score (KSS). The KSS is an examiner-administrated standard clinical evaluation tool reporting results for patients undergoing TKA. It separates findings in the operated knee (kKSS) score from findings related to the patient's function (fKSS), which might be affected by co-morbidities. The two sub-scores are reported separately ranging from 0 points (worst result) to 100 points (best results), as well as summarized score, total KSS. Final grading of total KSS results Scores of 160 to 200 will be rated as excellent, 140 to 159 as good, 120 to 139 as fair, and less than 120 as poor.

次要结局

  • Comparison of Radiographic status(one year postoperatively)
  • Quality of Life [EQ-5D-5L](one year postoperatively)
  • Anterior knee pain(one year postoperatively)
  • Clinical outcome of the Knee Surgery measured by the Knee Society Score (KSS) (clinical component)(one year postoperatively)
  • (Serious) Adverse Events(During the course of the study up to one year postoperatively)
  • Survival of the implant components(one year postoperatively)
  • Comparison of Radiographic alignment(one year postoperatively)

研究点 (2)

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