NCT02231996Unknown不适用
Chronic Granulomatous Disease Study in China
Shanghai Children's Medical Center1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2014年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- times of pneumonia
研究概览
简要总结
CGD is a rare inherited primary immunodeficiency which is caused by the defect in one of the subunits of NADPH oxidase complex.We tend to collect and analyze Chinese CGD patients who are diagnosed in hospitals affiliated to Shanghai Jiao Tong University School of Medicine, including clinical feature, laboratory data and genetic information. we aim to find out clinical, distribution, genetic characteristic of CGD in Chinese population, etc., thus further improving the level of diagnosis and treatment for CGD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •x-linked and AR-linked Chronic Granulomatous Disease
- •history of life-threatening severe infections
- •A functional assay demonstrating abnormal NADPH oxidase function or clinical history consistent with CGD
排除标准
- •Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for CGD.
结局指标
主要结局
times of pneumonia
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (1)
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