Haloperidol prophylaxis in older emergency department patients.
- Conditions
- Delirium
- Registration Number
- NL-OMON21334
- Lead Sponsor
- VU Univeristy Medical Center Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
1. Patients age 70 years or over;
2. First presentation in the ED in the last month;
Exclusion Criteria
1. Patients presenting in the ED with delirium according to the DSM-IV criteria;
2. Patients with clinically significant cardiac disorders:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence (percentage, %) and duration (days) of in-hospital delirium in both study arms (haloperidol and placebo group).
- Secondary Outcome Measures
Name Time Method 1. Number of delirium free days (days), which if in-hospital delirium develops, is defined by the number of days from hospital admission to the day delirium is diagnosed according to the DSM-IV;<br /><br>2. Mean hospital length-of-stay (days);<br /><br>3. Mortality (in-hospital, or during follow-up 3 or 6 months after hospital discharge);<br /><br>4. (I)ADL function;<br /><br>5. (Long-term) institutionalization (%);<br /><br>6. Cost effectiveness.