Efficacy Study of Minoxidil Lotion Versus Combined Minoxidil and Finasteride Lotion to Treat Male Pattern Hair Loss

Phase 3

Completed

• Conditions: Androgenetic Alopecia
• Interventions: Drug: 3%Minoxidil lotion; Drug: 3% Minoxidil with 0.1% Finasteride lotion

• Registration Number: NCT01391156
• Lead Sponsor: Mae Fah Luang University Hospital

Brief Summary

The purpose of this study is to compare the efficacy of 3% Minoxidil lotion and 3% Minoxidil with 0.1% Finasteride lotion for 6 months in male pattern hair loss.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Study First Submitted: 2011-07-01
• Study First Submitted QC: 2011-07-07
• Study First Posted: 2011-07-11
• Primary Completion: 2012-03
• Study Completion: 2012-03
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-19
• Last Update Posted: 2012-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• male, age 18-15 years
• androgenetic alopecia grade 3V to 5 ( Norwood-Hamilton classification)

Exclusion Criteria

• use minoxidil in 6 months
• use finasteride in 12 months
• use ketoconazole, tar, selenium shampoo, topical tretinoin, topical steroid in 2 weeks
• seborrheic dermatitis or psoriasis on scalp
• history of allergy to minoxidil, finasteride

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Minoxidil	3%Minoxidil lotion	-
MinoxidilFinasteride	3% Minoxidil with 0.1% Finasteride lotion	-

Primary Outcome Measures

Name	Time	Method
The mean change of hair count from baseline and 6 months	baseline and 6 months	Total hair count on the vertex is measured on 1 cm2 circular area. The mean change in hair count is compared at baseline and 6 months.The significance of change is determined by Unpaired t Test.

Secondary Outcome Measures

Name	Time	Method
Global photographic assessment by dermatologists	baseline and 6 months	Photographs of the vertex scalp are taken at baseline and 6 months. A panel of 3 dermatologists assesssed the change in hair growth using a 7-point scale.

Trial Locations

Locations (1)

Mae Fah Luang University Hospital(Bangkok); 🇹🇭 Bangkok, Thailand