The Learning Curve of NBI With Magnification in the Diagnosis of Colorectal Lesions

Completed

• Conditions: Colorectal Lesion

• Registration Number: NCT01431703
• Lead Sponsor: Zhizheng Ge

Brief Summary

It exists a learning curve in using NBI with magnification to differentiating colorectal lesions.

Detailed Description

It is very useful to use narrow-band imaging and Sano CP analysis in the differential diagnosis of colorectal lesions. The endoscopists who had never used NBI or no knowledge of NBI can have effective and stable diagnostic accuracy after using NBI with magnification to diagnose 15 target and non-target lesions respectively.

Study Timeline

• Study Start: 2010-05
• Primary Completion: 2011-04
• Study Completion: 2011-04
• Study First Submitted: 2011-09-08
• Study First Submitted QC: 2011-09-08
• Study First Posted: 2011-09-09
• Results First Submitted: 2016-04-26
• Status Verified: 2017-01
• Results First Submitted QC: 2017-01-08
• Last Update Submitted: 2017-01-08
• Results First Posted: 2017-03-01
• Last Update Posted: 2017-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 326

Inclusion Criteria

• Ages 16 to 85
• Any patient undergoing NBI with magnification colonoscopy exam and found with colorectal lesions

Exclusion Criteria

• Unwilling to consent
• Had surgery of colorectal tumors
• Using NSAIDS
• Diagnosed or suspected IBD
• Familial adenomatous polyposis(FAP) or hereditary non-polyposis colorectal(HNPCC) or other hereditary disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy, Sensitivity, and Specificity for Differentiating Neoplastic and Non-neoplastic Lesions	For this training, patients were consecutively enrolled until a total of 45 target and non-target lesions were obtained.