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Clinical Trials/NCT04644276
NCT04644276
Terminated
N/A

Feasibility Study of a Mask Adhesive in Patients Treated With NIV in an Institutional Setting

Philips Clinical & Medical Affairs Global1 site in 1 country7 target enrollmentFebruary 17, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Respiratory Failure
Sponsor
Philips Clinical & Medical Affairs Global
Enrollment
7
Locations
1
Primary Endpoint
Medical Adhesive-Related Skin Injury (MARSI)
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

To reduce interface leak and aerosol spread, Philips has developed an accessory to non-invasive ventilation(NIV) masks to be used with the Philips AF531 and the PerformaTrak mask on respiratory failure patients. For the purposes of capturing initial mask leak and safety data, this trial will enroll patients treated with NIV in an institutional setting (i.e., sleep lab).

Detailed Description

The Mask Adhesive will serve as an accessory to the AF531/PerformaTrak masks with the intention to reduce patient leak while a patient is receiving therapy. This accessory is a double-sided adhesive; with one side applied directly to the patient's skin and the other side connected to the mask cushion. Each adhesive is only to be applied to a patient once. The AF531/Performatrak mask can be removed from the adhesive and then re-applied, as necessary. For example, if the patient needs to remove the mask to eat or take medicine, the mask is removed from the patient and the adhesive will stay on the patient's face

Registry
clinicaltrials.gov
Start Date
February 17, 2021
End Date
December 9, 2021
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adults patients age 18 to 85 (inclusive)
  • Adult patients treated with NIV
  • Able to read, write, and speak English
  • Able to provide written informed consent
  • Willing to have facial hair removed for adhesive placement (if required)

Exclusion Criteria

  • Pre-existing allergy to tape or adhesive;
  • Blisters, open skin or pre-existing skin condition that may impact the ability to support removal of the mask adhesive without tearing the skin
  • pregnant (for females of childbearing age);
  • Individuals sentenced to such an institution under a criminal or civil statute,
  • Individuals detained in other facilities by virtue of statutes or commitment procedures which provide alternatives to criminal prosecution or incarceration in a penal institution, and individuals detained pending arraignment, trial, or sentencing

Outcomes

Primary Outcomes

Medical Adhesive-Related Skin Injury (MARSI)

Time Frame: Up to 5 business days

Percentage of patients who have severe and extreme skin irritation that persists for ≥ 30 min after mask adhesive removal (score of ≥ 3 on a 5-point grading system).

Clinician Ease of Use

Time Frame: Initial Impressions at Baseline and Overall Impressions at Study Completion (After at least two mask applications)

Clinician-perceived mask adhesive ease-of-use as measured by a 0-10 Likert Scale at baseline (initial impressions) and study completion (overall impressions) Specifically, the item, "How would you rate the ease of application of the adhesive to the mask?" (On a 0 to 10 scale, with 0=Extremely Difficult and 10=Extremely Easy)

Secondary Outcomes

  • Leak Change(Up to 5 business days)

Study Sites (1)

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