Diagnosis of acute kidney injury in patients undergoing off-pump coronary artery bypass

Phase 2

• Conditions: Kidney injury.; Chronic kidney disease, unspecified

• Registration Number: IRCT2014041813159N3
• Lead Sponsor: Vice Chancellor for Research, Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 966

Inclusion Criteria

?patients after undergoing elective on-?pump coronary ?bypass. Exclusion criteria: Emergency surgical operation; Previous history of ?cardiac surgery; American Society of Anesthesiologists Class (ASA) more than 4; Previous history of ?kidney diseases; Diabetic nephropathy; Preoperative serum creatinine level more than 1.3; ?Preoperative glomerular filtration rate (GFR) less than 75%, 8) preoperative ejection fraction ??(EF) less than 30%; Drainage more than the volume during the surgery; Use of a balloon pump ?during or after the surgery; Prolonged recurrent ventricular fibrillation (VF) during the surgery; ?High dose inotrope (inotrope 2) during the surgery; Lack of patient’s consent to participate in ?the study.?
Patients are also excluded during the study period if hyperchloremia (CL more than 110) occurs ?in the ICU, Various complications might occur (hemorrhage, drainage, cardiac arrest, ?prolonged hemodynamic instability, and neurological complications of CVA), which result in the ?exclusion of patients from the study.?

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial blood gases. Timepoint: Before and at the first 24 hours after intervention, every 4 hours. Method of measurement: Blood test.;Blood urea nitrogen?. Timepoint: Before and after intervention, daily. Method of measurement: Venous blood samples from the arm.;Blood creatinine level. Timepoint: After intervention, daily. Method of measurement: Blood test, jaffe method.;Sodium. Timepoint: Before and at the first 24 hours after intervention, every 4 hours. Method of measurement: Blood test.;Lactate. Timepoint: Before and after intervention, daily. Method of measurement: Blood test.

Secondary Outcome Measures

Name	Time	Method
Chlorine. Timepoint: Daily after intervention. Method of measurement: Blood test.