Pilotstudy to Develop a Guideline for Hometitration With Doudopa for Patients With Parkinson Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Patient satisfaction
研究概览
简要总结
The purpose of this study is to
- Create a guide for hometitration of Duodopa for patients with Parkinson's disease
- Outline which patients could be considered for "hometitration"
详细描述
To start treatment with continuous intestinal levodopa infusion to the duodenum (Duodopa-pump) in patients with Idiopathic Parkinson Disease (IPD), it is usually required that the patient is hospitalised to test if Duodopa works for the patient and for the titration process to find the relevant dosage before operation and connection of the pump.
A hospitalisation is very costly. Experience shows, that this group of patients are often very stressed during hospitalisation because of noise, impaired sleep and unfamiliar surroundings. These conditions make fast and effective dosage titration very difficult, and experience also shows that the dosage often needs to be recalibrated once the patient is back home in familiar surroundings.
The use of TeleMedicin (TM) is on the rise in Denmark as well as other international health care systems.
These factors were the basis for the home-titration study where patients have their initial dosage titration done in their own home, supported by one visit from nursing staff, and one TM (video consultation) a day. The goal is to make the titration process more effective, reduce cost by treating the patient in their own home and making the patient more satisfied with the titration process.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patients not eligible for Duodopa-treatment
结局指标
主要结局
Patient satisfaction
时间窗: 14 days after titration
Satisfaction questionnaire specific for study. 10 questions with a scale from highly satisfied to not at all satisfied.
次要结局
- Unified Parkinsons Disease Rating Scale III (UPDRS)(2 month)
- Hoehn Yahr staging of Parkinson's disease(2 month)
- Montreal Cognitive Assesment (MOCA)(2 month)
- Parkinsons Disease Questionnaire 39 (PD-Q39)(2 month)
- Barthel-20 index(2 month)
- Non-Motor Symptom Scale (NMSS)(2 month)
研究者
Bo Biering-Soerensen
Attending
Rigshospitalet, Denmark
