Effectiveness of Rohithakadi yogam in Cholelithiasis

Cholelithiasis is the medical term for gallstones. Gallstones are crystallized deposits forming

in the gallbladder or biliary tree primarily composed of cholesterol bilirubin and bile. These

stones often remain asymptomatic detected incidentally during imaging. However when

gallstones become larger or when they begin obstructing bile ducts symptoms or attacks

begin to occur such as steady severe pain in the upper abdomen that increases rapidly and may

last from 30 minutes to several hours radiate between the shoulder blades and right shoulder.

Gallstone is a common public health problem especially in developed countries. In India

cholelithiasis affects approximately 4 to 20 percentage of the population with a higher prevalence among

females and individuals with sedentary lifestyles.

In Ayurveda cholelithiasis gallstones is understood as a result of dosha imbalance

primarily Pitta and Kapha along with impaired digestion and accumulation of Ama  toxins.

Contributing factors include excessive intake of heavy oily sweet foods guru snigdha

madhura ahara irregular eating habits and sedentary lifestyle.

The gallbladder is referred to as Pittashaya in Ayurveda as per WHO International standard

terminology. Thus some Ayurveda physicians utilize the term Pittashaya ashmari for

gall bladder stone as the stone which is formed inside pittashaya. Classical texts like Charaka

Samhita and Ashtanga Hridaya mention a condition called Rudda-patha-Kamala which may

relate to gallstones obstructing bile flow.

This study aims to evaluate the effect of Rohithakadi Yogam a classical Ayurvedic polyherbal

formulation in the management of cholelithiasis Participants aged 20 to 60 years irrespective

of gender and meeting inclusion criteria will be selected from the study setting.  Each

participant will undergo a detailed clinical evaluation and relevant laboratory investigations.

Informed consent will be obtained before enrolment.  The intervention group will receive two

500 mg Rohithakadi Yogam tablets twice daily morning and evening before food for 90

days. The collected data will be subjected to statistical analysis to assess the safety and efficacy

of Rohithakadi Yogam in the management of cholelithiasis.