NCT02954094进行中（未招募）不适用
A Longitudinal Observational Study of the Natural History and Management of Patients With Hepatocellular Carcinoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 10,000
- 试验地点
- 71
- 主要终点
- Establish a longitudinal observational cohort to understand the natural history and management of HCC, including the safety and outcomes of HCC treatment interventions utilized in usual clinical practice
研究概览
简要总结
TARGET-HCC is a longitudinal, observational study of patients being managed for HCC in usual clinical practice. TARGET-HCC will create a research registry of participants with HCC within academic and community real-world practices in order to assess the safety and effectiveness of the entire spectrum of current and future therapies across diverse populations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female patients, age ≥18 years
- •Patients with a histological/cytological or radiological diagnosis of HCC (mixed HCC cholangiocarcinoma may be included; patients who are candidates for surgical and non-surgical treatment, as well as those being followed without specific HCC therapy may be included)
排除标准
- •1. Inability to provide written informed consent
结局指标
主要结局
Establish a longitudinal observational cohort to understand the natural history and management of HCC, including the safety and outcomes of HCC treatment interventions utilized in usual clinical practice
时间窗: Up to 15 years
次要结局
- Evaluate the impact of HCC treatment interventions and concomitant medications on comorbid conditions and liver function(Up to 15 years)
- Evaluate patient-reported outcomes measures during the natural course of HCC and management with HRQoL questionnaires(Up to 15 years)
- Establish a Biorepository Specimen Bank (BSB)(Up to 15 years)
研究者
研究点 (71)
Loading locations...
相似试验
已完成
不适用
Long-term Management of Patients With Ruptured HCCHepatocellular CarcinomaNCT06505291University Hospital, Caen112
终止
不适用
An Observational Study of Patients With Chronic Hepatitis B (CHB) InfectionLiver DiseasesHepatitisHepatitis BNCT03692897Target PharmaSolutions, Inc.1,708
招募中
不适用
A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)Nonalcoholic Fatty LiverNonalcoholic SteatohepatitisNCT02815891Target PharmaSolutions, Inc.15,000
已完成
不适用
Observational Study of People Living With HIV Treated With CD19-directed CAR T CellLeukemia, LymphoblasticLeukemiaLymphoma, Large B-Cell, DiffuseLymphoma, B-CellLymphoma, FollicularLymphoma, Non-HodgkinHIV Associated LymphomaFollicular LymphomaHIV Disease LymphomaHIV InfectionsNCT05784415AIDS Malignancy Consortium30
终止
不适用
Safety and Efficacy of Lenvatinib in Subjects With HCC Progression After First Line Treatment With Checkpoint InhibitorsHepatocellular CarcinomaNCT04428437Humanity & Health Medical Group Limited17