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Clinical Trials/NCT04287439
NCT04287439
Completed
Not Applicable

Progressive Muscle Relaxation and Mindfulness Meditation on Neuropathic Pain, Fatigue and Quality of Life in Type 2 Diabetes Patients: A Randomized Clinical Trial

Hacettepe University1 site in 1 country77 target enrollmentJune 8, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neuropathy, Diabetic
Sponsor
Hacettepe University
Enrollment
77
Locations
1
Primary Endpoint
Change in pain severity
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Patients with painful diabethic peripheral neuropathy will be entered.. Participants will be randomized to one of three study arms: Arm 1: relaxatio; Arm 2:meditation Arm 3: Attention matched control Hypothesis: Progressive muscle relaxation and mindfullness meditation will decrease severity of neuropathc pain and fatigue and improve quality of life.

Detailed Description

Previous reports have revealed that progressive muscle relaxation and meditation are promising for glycemic control in type 2 diabetes patients. On the other hand, research examining effects of these approaches on painful diabetic peripheral neuropathy, fatigue and quality of life is limited. The present study investigates the effects of progressive muscle relaxation and mindfullness meditation in a single-site, 3-arm, assessor blinded randomized, controlled study of 77 type 2 diabetes patients with painful diabetic peripheral neuropathy. Arm 1: relaxation; Arm 2: mindfulness meditation; Arm 3: Attention matched control. The investigators hypothesize that Progressive muscle relaxation and mindfulness meditation will decrease severity of neuropathic pain and fatigue and improve quality of life.

Registry
clinicaltrials.gov
Start Date
June 8, 2018
End Date
November 17, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nur Izgu

Assistant professor

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • being diagnosed with painful diabethic peripheral neuropathy ,
  • being at least primary school graduates,
  • not using any other complementary or integrative therapy during the study period

Exclusion Criteria

  • neuropathy history due to any other causes such as megaloblastic anemia, fibromyalgia, autoimmune diseases, hypothyroidism, and lumbar disc hernia
  • having end-stage of renal failure, chronic obstructive pulmonary disease, advanced cardiac failure, musculoskeletal disorders or depression
  • having a diabetic foot ulcer or amputation.

Outcomes

Primary Outcomes

Change in pain severity

Time Frame: Baseline measurements, at the end of 12th week and two weeks after the completion of the interventions

Pain severity will be measured based on patient report by a visual analog scale. Higher score means increase in pain severity.

Secondary Outcomes

  • Change in Quality of life status(baseline measurements, at the end of 12th week and two weeks after the completion of the interventions)
  • Change in fatigue severity(Baseline measurements, at the end of 12th week and two weeks after the completion of the interventions)

Study Sites (1)

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