ACTRN12615001219572已完成4 期
A randomized controlled trial of intensive urate-lowering therapy for bone erosion in tophaceous gout
niversity of Auckland0 个研究点目标入组 104 人开始时间: 2015年11月9日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 104
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 19 Years 至 o limit（—）
- 性别
- All
入选标准
- •Gout, as defined by the 2015 ACR-EULAR classification criteria
- •At least one bone erosion on plain radiographs of the feet
- •Age over 18 years
- •Able to provide informed consent
- •On oral urate-lowering therapy
- •Serum urate concentrations at or above 0.30mmol/L
排除标准
- •Stage 4 or 5 chronic kidney disease (estimated glomerular filtration rate (eGFR) <30mls/min/1.73m2)
- •Pregnancy or breastfeeding
- •Unstable systemic medical condition
- •On azathioprine (due to potential interactions with both allopurinol and febuxostat)
- •On warfarin
研究者
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