Evaluation of the Proliferative Activities of Insulin Analogues in Primary Human Tumor Cells

• Conditions: Endometrial Cancer; Colon Cancer

• Registration Number: NCT01267461
• Lead Sponsor: Meir Medical Center

Brief Summary

Recently the general medical literature has become aware that the use of certain long-acting insulin analogues could potentially increase cancer risk.During the last few years the investigators group generated information of both scientific and clinical relevance on the proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is to evaluate the hypothesis that the proliferative and signalling activities elicited by insulin analogues may have a impact on tumor behavior. In this study the investigators will asses the biological actions of insulin analogs in primary tumor cells of endometrial and colon cancer.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-12-27
• Study First Submitted QC: 2010-12-27
• Study First Posted: 2010-12-28
• Status Verified: 2012-08
• Last Update Submitted: 2012-08-09
• Last Update Posted: 2012-08-10

Recruitment & Eligibility

• Status: AVAILABLE
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• Patients with Endometrial and Colon Cancer

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Exclusion Criteria

• None

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Study & Design

• Study Type: EXPANDED_ACCESS
• Study Design: Not specified