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Clinical Trials/RBR-2dxyx4
RBR-2dxyx4
Not yet recruiting
未知

Mechanical ventilator for use in patients with respiratory failure due to Covid-19

Hospital Universitário Clementino Fraga Filho0 sitesJune 2, 2020

Overview

Phase
未知
Intervention
Not specified
Conditions
Respiration, Artificial
Sponsor
Hospital Universitário Clementino Fraga Filho
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 2, 2020
End Date
TBD
Last Updated
2 years ago
Study Type
Intervention

Investigators

Sponsor
Hospital Universitário Clementino Fraga Filho

Eligibility Criteria

Inclusion Criteria

  • Adults age greater than or equal to 18 years ;patients assisted in the ER with probable or confirmed infection by COVID\-19; time between symptoms and inclusion less than or equal to 7 days; present mild symptoms, with no indication of hospitalization; present at least 1 risk factor for complication (age more than 65 years; hypertension; diabetes mellitus; bronchial asthma; COPD or other chronic lung diseases; smoking
  • ; immunosuppression; obesity

Exclusion Criteria

  • Patients under 18 years old, hospitalization in the first care; positive test for influenza in the first visit; known hypersensitivity hydroxychloroquine / chloroquine; previous diagnosis of retinopathy or macular degeneration; previous diagnosis of QT\-long syndrome; history of sudden death in close family members (parents and siblings), use of anti\-arrhythmic drugs or others that may increase the bioavailability of hydroxychloroquine or enhance its effect, decompensated heart failure, symptomatic coronary artery disease; evidence of known liver disease, reported by the patient; evidence of known chronic kidney disease, reported by the patient, patients with pancreatitis, baseline ECG with QT interval greater than or equal to 480ms; chronic use of hydroxychloroquine / chloroquine for other reasons; pregnancy

Outcomes

Primary Outcomes

Not specified

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