Management of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosol

Kliniken Valens0 个研究点目标入组 40 人开始时间: 2020年2月21日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Male and female persons with neurogenic dysphagia who receive a video endoscopic swallowing examination (FEES) in the Klinik Valens
•? Age> 18 years
•? Diagnoses: stroke (infra- or supratentorial), Parkinson's syndrome (idiopathic Parkinson's syndrome, multi-system atrophy, progressive supranuclear palsy, corticobasal degeneration, Lewy-body dementia), intracerebral hemorrhage, traumatic brain injury (without critical illness polyneuro- / -Myopathy)
•? 1 out of 4 signs of dysphagia (rattling noises in the airways, moist voice sound at rest or after eating, coughing when taking solid and liquid food, recurrent respiratory infections)
•? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak Cough Flow> 2.7 l / s (160 l / min)
•? Patients who are unable to completely eliminate pharyngeal residuals using arbitrary clearing maneuvers (compensation strategies, night drinking, throat clearing, swallowing, reflex swallowing / coughing) or after reflex cough caused by food / liquid aspiration / penetration
•? Written consent of the test subjects after the information has been given

•Patients with structural dysphagia (e.g. trauma, tumor, radiation)
•Complication-free, requirement-covering food and liquid intake
•Patients with chronic respiratory diseases
•? Patients with severe cardiovascular diseases including uncontrolled arterial hypertension
•? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak cough flow <2.7 l / s (160 l / min)
•? Diagnoses: Neuromuscular Diseases, Encephalomyelitis Disseminata, Critically Illness Polyneuro - / - Myopathy
•? Patients without pharyngeal residuals
•disturbed nose anatomy

发起方