Management of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosol

Not Applicable

• Conditions: R13; Dysphagia

• Registration Number: DRKS00020893
• Lead Sponsor: Kliniken Valens

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-21
• Study Completion: 2022-09-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Male and female persons with neurogenic dysphagia who receive a video endoscopic swallowing examination (FEES) in the Klinik Valens
? Age> 18 years
? Diagnoses: stroke (infra- or supratentorial), Parkinson's syndrome (idiopathic Parkinson's syndrome, multi-system atrophy, progressive supranuclear palsy, corticobasal degeneration, Lewy-body dementia), intracerebral hemorrhage, traumatic brain injury (without critical illness polyneuro- / -Myopathy)
? 1 out of 4 signs of dysphagia (rattling noises in the airways, moist voice sound at rest or after eating, coughing when taking solid and liquid food, recurrent respiratory infections)
? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak Cough Flow> 2.7 l / s (160 l / min)
? Patients who are unable to completely eliminate pharyngeal residuals using arbitrary clearing maneuvers (compensation strategies, night drinking, throat clearing, swallowing, reflex swallowing / coughing) or after reflex cough caused by food / liquid aspiration / penetration
? Written consent of the test subjects after the information has been given

Exclusion Criteria

Patients with structural dysphagia (e.g. trauma, tumor, radiation)
• Complication-free, requirement-covering food and liquid intake
• Patients with chronic respiratory diseases
? Patients with severe cardiovascular diseases including uncontrolled arterial hypertension
? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak cough flow <2.7 l / s (160 l / min)
? Diagnoses: Neuromuscular Diseases, Encephalomyelitis Disseminata, Critically Illness Polyneuro - / - Myopathy
? Patients without pharyngeal residuals
• disturbed nose anatomy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br>It is being examined whether the patients can now, through the reflective cough, remove the pharyngeal residues by swallowing or spitting out or whether they can be obtained by the authorities, so that the risk of developing aspiration pneumonia can be improved.

Secondary Outcome Measures

Name	Time	Method
<br>If pharyngeal residues still exist after one of the cough stimulations mentioned has been used, a crossover is used for ethical reasons and the respective intervention is used in the other group.