Is walking really the best therapy for walking recovery after stroke?

Not Applicable

• Conditions: Walking recovery after stroke; Stroke - Ischaemic; Stroke - Haemorrhagic; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12613000994785
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-09-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Between 3 months and 2 years post-stroke
Overground gait velocity between 0.6 and 1.0 m/s

Exclusion Criteria

Less than 3 months or greater than 2 years post-stroke
Patient receiving other walking therapy
Brain stem stroke
Orthopaedic conditions that would affect gait patterns
Co-morbidities that would restrict walking such as cardio-pulmonary disease and morbid obesity
Vision deficits, apraxia, or neglect that would be a barrier to training
Mini-Mental State Exam score < 20
Cognitive or communication deficits that preclude informed consent and study engagement
Contraindications to TMS

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fast self-selected walking speed using the 10 m walk test.[At two-month followup visit];Depth of reciprocal inhibition between ankle effectors using 1 ms pulse-width suprathreshold electrical stimulation of an antagonist's mixed peripheral nerve on EMG recorded from weak tonic contraction of the agonist.[Two-month followup visit.]

Secondary Outcome Measures

Name	Time	Method
Stroke Specific Quality of Life Scale [Two-month followup visit];Spatiotemporal gait measures will be measured using a 5 m long GaitRite instrumented mat.[Two-month followup visit];TMS-conditioned H-reflexes measure the strength of conductivity between motor cortex and spinal circuits. Transcranial magnetic stimulation is delivered to the lower limb motor cortex at a point in time that allows the descending volley to arrive at the spinal cord circuitry when an H-reflex is being generated at the spinal cord level. H-reflexes are elicited in the soleus muscle using electrical stimulation of the posterior tibial nerve. The extent of modulation of the TMS conditioned H-reflex can be taken as a measure of cortex to spinal cord conductivity. [Two-month followup visit]