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临床试验/NCT03538197
NCT03538197已完成不适用

SURAYA : Suicide Re Attempts in Young Adults After First Suicide Attempt : Socio-demographic, Clinical and Biological Correlates

Hôpital le Vinatier2 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2018年5月22日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
200
试验地点
2
主要终点
Assessment of the prevalence of SR rate over a 3-months period after the first suicide attempt, among young adults aged 18 to 25.

研究概览

简要总结

Suicide is the second leading cause of death among people aged 15 to 24 (WHO, 2014). After a first suicide attempt, the 18 to 25 years old would be very likely to repeat the act: 25 to 31% would make a new attempt in the following year (Christiansen et al, 2007).

Nevertheless the literature on this subject is not detailed. In this project, we hypothesize that young adults aged 18 to 25 who have made their first suicide attempt will repeat their act more frequently than younger or older populations. In addition, these young people would have identifiable risk factors (sociodemographic, clinical and biological) that differ from young people who do not enter this phenomenon.

Our main objective is to measure the rate of suicidal reiteration in a population of young adults aged 18 to 25 years.

Our secondary objectives are to identify sociodemographic, clinical and biological characteristics of a population of suicidal re attempt young people, to highlight potential risk factors

详细描述

Objectives:

  • Our main objective is to measure the rate of suicidal re attempt (SR) in a population of young adults aged 18 to 25 years.
  • Our secondary objectives are to identify sociodemographic, clinical and biological characteristics of a population of suicidal young people, in an attempt to highlight potential risk factors. We will try to highlight correlations between the reiteration of the suicidal act and:
  1. socio-demographic criteria: level of urbanity, socio-economic level, social and family context, date and place of birth, religion, sexual orientation, name and contact details of the general practitioner, previous access to care
  2. scores on the scales of various psychiatric pathologies, existing or in formation (eg depression, anxiety disorders, psychosis)
  3. alterations at the peripheral level
  • on the stress response system: cortisolemia and capillary cortisol levels
  • on the total and mature serum BDNF

In addition, DNA and RNA genetic samples will be taken in order to constitute a biological collection for later research.

Type of study: This is an interventional research with minimal risks and constraints (2 ° study), multicenter prospective cohort.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 25 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • between the ages of 18 and 25
  • a first suicide attempt
  • Master French sufficient

排除标准

  • Majors protected: under curatorship or under guardianship

结局指标

主要结局

Assessment of the prevalence of SR rate over a 3-months period after the first suicide attempt, among young adults aged 18 to 25.

时间窗: Within the first 3 months following a first suicide attempt

次要结局

  • STAXI-2(Within the first 3 months following a first suicide attempt)
  • Analog visual scales(Within the first 3 months following a first suicide attempt)
  • CTQ : childhood trauma questionnary(Within the first 3 months following a first suicide attempt)
  • date of birth(Within the first 3 months following a first suicide attempt)
  • mature and total BDNF(Within the first 3 months after the first suicide attempt)
  • level of urbanity(Within the first 3 month following a first suicide attempt)
  • place of birth(Within the first 3 months following a first suicide attempt)
  • PQB : psychosis risk screening(Within the first 3 months following a first suicide attempt)
  • AUDIT : Alcohol use disorders test(Within the first 3 months following a first suicide attempt)
  • CUDIT : Cannabis use Disorders Identification Test(Within the first 3 months following a first suicide attempt)
  • Fagerstrom Questionary(Within the first 3 months following a first suicide attempt)
  • The reasons for living inventory(Within the first 3 months following a first suicide attempt)
  • C-SSRS : Colombia Suicide Severity Rating Scale(Within the first 3 months following a first suicide attempt)
  • hair cortisol and blood cortisol(Within the first 3 months following a first suicide attempt)
  • Negative life events during the last 6 months(Within the first 3 months following a first suicide attempt)
  • QIDS : Quick Inventory of Depressive Symptomatology(Within the first 3 months following a first suicide attempt)
  • MDQ : Mood disorder questionnaire(Within the first 3 months following a first suicide attempt)
  • CAST : Cannabis Abuse Screening Test(Within the first 3 months following a first suicide attempt)
  • socio-economic level(Within the first 3 month following a first suicide attempt)
  • social and family context(Within the first 3 months following a first suicide attempt)
  • BIS : Barratt Impulsive Scale(Within the first 3 months following a first suicide attempt)

研究者

发起方
Hôpital le Vinatier
申办方类型
Other
责任方
Sponsor

研究点 (2)

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