Expiratory Flow Limitation and Postoperative Complications
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Respiratory Complications
- Sponsor
- Università degli Studi di Ferrara
- Enrollment
- 330
- Locations
- 1
- Primary Endpoint
- Pulmonary complication
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital
Investigators
Savino Spadaro
Universitary Researcher
Università degli Studi di Ferrara
Eligibility Criteria
Inclusion Criteria
- •General anesthesia
- •Duration of the surgery \>2 hours
Exclusion Criteria
- •\<18 years
- •Consensus not given
Outcomes
Primary Outcomes
Pulmonary complication
Time Frame: 28 days
Postoperative pulmonary complication such infection, acute respiratory distress, post operative desaturation