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临床试验/NCT02229591
NCT02229591已完成不适用

Expiratory Flow Limitation and Postoperative Complications

Università degli Studi di Ferrara1 个研究点 分布在 1 个国家目标入组 330 人开始时间: 2013年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
330
试验地点
1
主要终点
Pulmonary complication

研究概览

简要总结

Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • General anesthesia
  • Duration of the surgery >2 hours

排除标准

  • <18 years
  • Consensus not given

结局指标

主要结局

Pulmonary complication

时间窗: 28 days

Postoperative pulmonary complication such infection, acute respiratory distress, post operative desaturation

次要结局

未报告次要终点

研究者

发起方
Università degli Studi di Ferrara
申办方类型
Other
责任方
Principal Investigator
主要研究者

Savino Spadaro

Universitary Researcher

Università degli Studi di Ferrara

研究点 (1)

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