Expiratory Flow Limitation and Postoperative Complications
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 330
- 试验地点
- 1
- 主要终点
- Pulmonary complication
研究概览
简要总结
Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •General anesthesia
- •Duration of the surgery >2 hours
排除标准
- •<18 years
- •Consensus not given
结局指标
主要结局
Pulmonary complication
时间窗: 28 days
Postoperative pulmonary complication such infection, acute respiratory distress, post operative desaturation
次要结局
未报告次要终点
研究者
Savino Spadaro
Universitary Researcher
Università degli Studi di Ferrara
