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Clinical Trials/NCT03260582
NCT03260582
Completed
N/A

Implementation and Assessment of a Life-style Focused Patient Support Application (App) and Activity Trackers for Improving Risk Factor Management, Physical Activity, Quality of Life and Prognosis in Post-myocardial Infarction Patients

Lund University2 sites in 1 country150 target enrollmentApril 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Myocardial Infarction
Sponsor
Lund University
Enrollment
150
Locations
2
Primary Endpoint
Change in submaximal exercise capacity in watts (W)
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The study will assess the efficacy of a web-based application as a complement to traditional exercise-based cardiac rehabilitation for improvement of secondary prevention outcomes in post-myocardial infarction patients, compared with usual care. The hypothesis is that the intervention enhances patient adherence to lifestyle advice (exercise training, daily physical activity, healthy diet and tobacco abstinence) and medication, resulting in better risk factor control and prognosis as well as increased self-rated health.

Detailed Description

It is well documented that participation in cardiac rehabilitation (CR) programs improves risk factor control and therapy adherence, enhances quality of life and reduces recurrent events. However, the current incomplete fulfilment of guideline recommended CR targets is a matter of concern. Also, while international recommendations advocate program flexibility and individual tailoring, most of the current CR programs are rigid, time-limited and demand substantial health care resources. Therefore, all main international heart associations have claimed for the reengineering of CR to enhance access, adherence, and effectiveness. The general call is for the development of innovative and cost-effective CR programs oriented to modify lifestyle and behaviour with sustainable results and that may be easily integrated in the pre-existing health care structures.eHealth i.e. the use of electronic communication and information technologies in health care, offers a whole new array of possibilities to provide clinical care. These include for example distance monitoring via telecommunication and sensors, interactive computer programs and smart phone applications. While there are thousands of available eHealth applications on the market, only a small minority have been tested in a controlled manner with proper guidance from health care personnel. The study will assess the efficacy of a web-based patient support application as a complement to traditional exercise-based CR for improvement of secondary prevention outcomes in post-MI patients, compared with usual care. The hypothesis is that the intervention enhances patient adherence to lifestyle advice (exercise training, daily physical activity, healthy diet and tobacco abstinence) and medication, resulting in better risk factor control and prognosis as well as increased self-rated health. A secondary hypothesis is that complementing the application with an activity tracker (accelerometer in a smart bracelet) will enhance the effect of the intervention.

Registry
clinicaltrials.gov
Start Date
April 2016
End Date
June 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in submaximal exercise capacity in watts (W)

Time Frame: Change between first (2-4 weeks post-MI) and second (4-6 months post-MI) submaximal exercise test conducted at physiotherapist visits

Submaximal exercise capacity reflects the patients´ level of physical fitness.The submaximal exercise test is performed on a bicycle ergometer according to the World Health Organisation (WHO) protocol, with an increased workload of 25W every 4.5 minutes The initial starting load, 25W or 50W, is decided, based on the patient's exertion history. After two and four minutes of each workload; heart rate, rate of perceived exertion according to Borg's rating of perceived exertion scale (RPE) and subjective symptoms, including chest pain and dyspnea according to Borg's Category Ratio Scale, CR-10, scale are rated. After three minutes, the systolic blood pressure is registered. The exercise test is discontinued at Borg RPE 17 and/or dyspnea 7 on Borg's CR-10 scale.

Secondary Outcomes

  • Change in LDL cholesterol(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in HDL cholesterol(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in diastolic blood pressure(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in total cholesterol(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in BMI(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in waist circumference(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in systolic blood pressure(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in self-reported health(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in healthy diet index(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Smoking habits(First (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in weight(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in triglycerides(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in fasting plasma glucose(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Change in hemoglobin A1c(Change between baseline, first (6-8 weeks post-MI) and second (12-14 months post-MI) nurse visits post-MI)
  • Changes in self-reported physical activity(Change between baseline, first (2-4 weeks post-MI) and second (4-6 months post-MI) physiotherapist visits post-MI)
  • Uptake(Six months)
  • Adherence(Six months)
  • Number of contacts with the CR staff(12-14 months)
  • Incident cardiovascular events at one year(One year)
  • Incident cardiovascular events at three years(Three years)

Study Sites (2)

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