NCT03602482已完成不适用
Standing Cognition and Co-morbidities of POTS Evaluation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 139
- 试验地点
- 2
- 主要终点
- Executive Function (Stroop Word-color Test)
研究概览
简要总结
The purpose of this study is to evaluate cognition in patients with postural tachycardia syndrome (POTS) while lying down and standing and to assess the prevalence of hypermobile Ehlers-Danlos Syndrome in POTS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Previously diagnosed with POTS, or healthy control
- •Age between 13-60 years
- •Participants may be any race, ethnicity, sex, or gender
- •Able and willing to provide informed consent
排除标准
- •Inability to give, or withdrawal of, informed consent
- •Age ≤ 13 or ≥ 61 years
- •Prisoners
- •Unable to stand
结局指标
主要结局
Executive Function (Stroop Word-color Test)
时间窗: 1 hour
Testing scores are normalized using T-scores for predicted values based on age and education for each participant. Scores range from 0 to 100. Higher numbers indicate better cognition. Testing will be performed while participants are supine and standing.
次要结局
- Attention Score Using Cogstate Identification Task(1 hour)
- Number of Participants With Hypermobile Ehlers-Danlos Syndrome (hEDS)(1 hour)
- Heart Rate Standing Minus Heart Rate Supine(1 hour)
研究者
Amanda Miller
Postdoctoral Fellow
Milton S. Hershey Medical Center
研究点 (2)
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