A randomised, controlled trial to compare the effects of systemic HRT (tibolone) and vaginal oestrogen (estring) upon the overactive bladder in postmenopausal women.
Not Applicable
Completed
- Conditions
- rological and Genital Diseases: Overactive bladderUrological and Genital DiseasesOther disorders of the bladder
- Registration Number
- ISRCTN74263041
- Lead Sponsor
- Department of Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
120 postmenopausal women aged 60 or over who are suffering from overactive bladder symptoms.
Exclusion Criteria
1. Women aged < 60 years
2. Pre-menopausal women
3. Women who have had a history of uncontrolled metabolic diseases, neurological conditions, permanent catheterisation, chronic urinary tract infections
4. Patients who have any contraindications to the use of HRT
5. Patients who have suffered a major prolapse (as defined by The International Continence Society)
6. Patients who have taken hormone replacement therapy within the last 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method