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A Randomized Controlled Study of Docetaxel Monotherapy or Docetaxel and DOXIL for the Treatment of Advanced Breast Cancer - DOXIL BCA

Phase 1
Conditions
Breast cancer
Registration Number
EUCTR2004-000617-19-ES
Lead Sponsor
J&JPRD, a division of Janssen-Cilag
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
0
Inclusion Criteria

- Female
- Age 18 years or older
- Advanced breast cancer (Stage IIIb, not amenable to surgical treatment or Stage IV), for which there is histologic or cytologic proof of malignancy
- Presence of measurable disease according to the Response Evaluation Criteria in Solid Tumors (RECIST) provided in Attachment 4, RECIST Criteria
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- More than 1 prior cytotoxic chemotherapy regimen for advanced breast cancer (this does not include treatment given in the neoadjuvant or adjuvant setting)
- Treatment of advanced breast cancer with an anthracycline, paclitaxel, docetaxel, vinorelbine, or vinblastine (prior treatment of advanced breast cancer with 1 regimen that includes alkylating agents or antimetabolite agents is acceptable)

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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