Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores
Not Applicable
- Conditions
- Anastomotic Leak
- Registration Number
- NCT04422106
- Lead Sponsor
- Mansoura University
- Brief Summary
Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application of scoring scale to assess presence or absence of leakage.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 118
Inclusion Criteria
- Any patient with intestinal or colonic anastomosis either elective or emergent.
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Exclusion Criteria
- Patients with inflammatory bowel disease will be excluded because this could influence plasma levels of inflammatory biomarkers.
- patients using corticosteroids
- Patients unfit for anaesthesia, those having collagen diseases or hematological disorders.
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Early detection and management of intestinal anastomotic leak 6 months Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leak(Intestinal fatty acid binding protein, Procalcitonin and CRP) with application of scoring scale(Dekker et al 2011) (Dulk et al ., 2013) to assess presence or absence of leakage.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mansoura University
🇪🇬Mansoura, Dakahlia, Egypt