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Postoperative Pain After Medical Abortion Under Local Anesthesia : Comparison of Several Analgesic Regimen

Not Applicable
Completed
Conditions
Abortion, Induced
Registration Number
NCT00188071
Lead Sponsor
University Hospital, Angers
Brief Summary

* To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics

* each treatment beeing allocated by randomization

Detailed Description

* 240 pregnant women who undewent a medical abortion by aspiration, under local anesthesia, (day case surgery) were enrolled after informed consent and signed approval

* according to randomization, they received one hour before medical abortion procedure performed under local anesthesia of the cervix, one of these three diffrente analgesics :

* paracetamol 1 gr

* ketoprofen 100 mg

* the association of both Postprocedure pain was recorded, by nurse, using a visual analog scale (VAS), 7 times before and after the procedure, until the discharge of the patient.

* if VAS was above 40 on two consecutive measurements a morphine injection was given.

* the number and total amount of morphine was recorded.

* satisfaction was recorded within the 3 postoperative day by a telephone inquiry.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
240
Inclusion Criteria
  • pregnant women
  • medical abortion performed in day case surgery under local anesthesia
  • informed written consent
Exclusion Criteria
  • under 18 year old

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
postoperative pain rating
Secondary Outcome Measures
NameTimeMethod
morphine consumption
patient satisfaction

Trial Locations

Locations (1)

Dept of Anesthesia - CHU

🇫🇷

Angers, France

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