Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin

Not Applicable

Completed

• Conditions: Skin Problems
• Interventions: Other: Emulsion base; Combination Product: Emulsion base with probiotics

• Registration Number: NCT03350893
• Lead Sponsor: GenMont Biotech Incorporation

Brief Summary

Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions. In this clinical study, the investigators researched the benefit effects of heat-killed Lactobacillus plantarum cream on skin health.

Detailed Description

To evaluate the efficacy of applying probiotic cream in the ameliorationof the whole face skin conditions such as moisturizing, whitening, anti-wrinkle and so on.

Study Timeline

• Study Start: 2017-09-18
• Study First Submitted: 2017-11-15
• Study First Submitted QC: 2017-11-17
• Study First Posted: 2017-11-22
• Primary Completion: 2018-07-25
• Study Completion: 2018-08-31
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-14
• Last Update Posted: 2019-08-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Healthy volunteers between the ages of 20-60.

Exclusion Criteria

• Subjects with photosensitivity (Sun allergy).
• Subjects are undergoing medical therapy for skin diseases.
• Subjects with severe hyperpigmentation.
• Subjects with diabetes.
• Subjects with cosmetics allergy.
• Subjects who have recently participated laser therapies or other treatments are not suitable for sun.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control Group	Emulsion base	Emulsion base without probiotics
Active Group	Emulsion base with probiotics	Emulsion base with probiotics

Primary Outcome Measures

Name	Time	Method
Skin Diagnosis	Baseline, 4 weeks and 8 weeks	The changes of skin condition by VISIA Complexion Analysis System

Secondary Outcome Measures

Name	Time	Method
Skin Moisture	Baseline, 4 weeks and 8 weeks	The changes of skin moisture by Skicon-200EX and Corneometer CM 825
Skin Color	Baseline, 4 weeks and 8 weeks	The changes of skin color by DermaSpectrometer

Trial Locations

Locations (1)

Chia Nan University of Pharmacy and Science; 🇨🇳 Tainan, Taiwan