EUCTR2015-005776-24-ES
Active, not recruiting
Phase 1
Intensive treatment of blood pressure in acute ischemic stroke. TICA 2 study.
Dr. Manuel Rodríguez Yáñez0 sitesMarch 1, 2016
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Acute ischemic stroke
- Sponsor
- Dr. Manuel Rodríguez Yáñez
- Status
- Active, not recruiting
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Men or women aged 18 and up to 85 years inclusive.
- •Diagnosis clinical and neuroimaging (CT or MRI) of ischemic stroke.
- •Ability to initiate antihypertensive treatment within 12 hours after the onset of symptoms (in the case of stroke, it is considered the start time as the time in which the patient has been asymptomatic last seen).
- •Participating with systolic blood pressure greater than or equal to 140 mm Hg and less than or equal to 220 mmHg at the time of inclusion.
- •Participant or able to understand the requirements of the study and sign the informed consent legal representative.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 40
- •F.1\.3 Elderly (\>\=65 years) yes
Exclusion Criteria
- •Uncontrollable hypertension (high SBP 220 mm Hg) or any condition that needs urgent antihypertensive treatment.
- •Having had a stroke in the last 90 days in the same territory as current stroke.
- •Having suffered a heart attack in the previous 90 days.
- •Suspected aortic dissection, or hypertensive encephalopathy.
- •Presence of intracerebral or subarachnoid hemorrhage in the basal neuroimaging (CT or MRI).
- •It is probable realization has been made or intra\-arterial recanalization techniques by the current stroke.
- •Occlusion or critical carotid stenosis known.
- •Be a candidate for carotid revascularization in the next three months.
- •previous alterations that, according to the investigator, may interfere with the interpretation of neurological scales.
- •Eat or low level of consciousness (defined as a score \= 2 in paragraph 1a of the NIHSS), dementia or mental impairment that judgment of the investigator makes the patient is unable to participate in the study.
Outcomes
Primary Outcomes
Not specified
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