Observation of the effect of acupuncture to regulate the stomach and intestines on the structure of intestinal flora in adolescents with mild to moderate depressio
Not Applicable
- Conditions
- Depression
- Registration Number
- ITMCTR2200005587
- Lead Sponsor
- The Second Affiliated Hospital of Zhejiang Chinese Medicine University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Patients who met the above diagnostic criteria; aged 12-18 years; conscious, with stable vital signs and some expressiveness; patients with mild to moderate depression with a Hamilton Depression Scale (HAMD) score between 20-35; and those who agreed to sign the informed consent form after approval by the ethics committee of the hospital.
Exclusion Criteria
Patients with secondary depression caused by other organic pathologies; those with severe heart, liver, lung or kidney dysfunction or serious diseases and those with infectious diseases; adolescent females in pregnancy or breastfeeding; those taking antibiotics, steroids, immunosuppressants, etc. 2 weeks prior to the assessment; those with severe suicidal self-abusive tendencies.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HAMD;ALFF\ReHo\FC;SDS;BDI-II;intestinal microbial communities;
- Secondary Outcome Measures
Name Time Method GABA;SCFAs;5-HT;CORT;NE;BDNF;DA;