A study on efficacy of fractional CO2 LASER with topical Latanoprost vs fractional CO2 LASER with topical Tofacitinib in stable vitiligo - An interventional study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Repigmentation will be assessed using dermoscopy and photographic assessment using MIISP score and GPA score
研究概览
简要总结
This study is to determine the efficacy of fractional CO 2 LASER with topical Latanoprost versus topical Tofacitinib in treatment of stable vitiligo patients, Fractional CO 2 LASER, Fractional CO2 LASER will be done every two weekly once at that time either of the two topical agents according to randomization will be given and patient will be advised to use the same topical agent till completion of 8 weeks. Topical Tofacitinib 2% and Topical Latanoptost are Melanocyte stimulating agents and hence are tried in treatment of vitiligo, as of now no study has compared these groups. Thus making this study first of its kind.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 6.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients above 6 years of age.
排除标准
- •Patients with keloidal tendency Pregnant or lactating women Patients with vitiligo associated syndromes Patients who are not willing to participate in study.
结局指标
主要结局
Repigmentation will be assessed using dermoscopy and photographic assessment using MIISP score and GPA score
时间窗: Baseline, 4weeks, 8weeks.
次要结局
- Adverse effects of fractional CO2 LASER, Tofacitinib, Latanoprost.(Before each sitting -every 2 weeks and)
研究者
Bommaka Sruthi
Sri Devaraj Urs Academy of Higher Education and Research