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Clinical Trials/NCT06226649
NCT06226649
Completed
Not Applicable

A Randomized Controlled Feasibility Trial Evaluating the Implementation of Digital Dyadic Empowerment Program (DDEP) on Lifestyle Modification for Chronic Kidney Disease Management

National Cheng Kung University1 site in 1 country120 target enrollmentJanuary 29, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Kidney Diseases
Sponsor
National Cheng Kung University
Enrollment
120
Locations
1
Primary Endpoint
Change From Baseline in eGFR at 3 Months (Patient-specific)
Status
Completed
Last Updated
last year

Overview

Brief Summary

This is a randomized controlled feasibility trial conducted on patients with Chronic Kidney Disease (CKD) and their significant other

Detailed Description

The trial will be conducted on 60 dyads, each comprising a CKD patient and a significant other, who will be randomly assigned into two groups. The intervention group will receive the Digital Dyadic Empowerment Program (DDEP) while the control group will receive routine education and care.

Registry
clinicaltrials.gov
Start Date
January 29, 2024
End Date
December 2, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Miaofen Yen

Professor, Department of Nursing, College of Medicine

National Cheng Kung University

Eligibility Criteria

Inclusion Criteria

  • The patient has a diagnosis of Chronic Kidney Disease for at least six months;
  • The patient can identify a helpful significant other and both parties are willing to participate;
  • The patient can communicate in Mandarin or Taiwanese.

Exclusion Criteria

  • The significant other is a healthcare provider;
  • The patient or the significant other has a mental illness diagnosis;
  • The patient is currently receiving renal replacement therapies.

Outcomes

Primary Outcomes

Change From Baseline in eGFR at 3 Months (Patient-specific)

Time Frame: Before initial intervention and 3 months after initial intervention

For each patient, change from Baseline (Followup score - Baseline score) in the estimated Glomerular Filtration Rate (eGFR) by the IDMS-MDRD Equation at 3 months was obtained through the patient's biochemical test reports. Higher eGFR numbers generally indicate better kidney functions.

Change From Baseline in CKD Stage at 3 Months (Patient-specific)

Time Frame: Before initial intervention and 3 months after initial intervention

For each patient, the change from Baseline in CKD stage at 3 months was obtained by comparing the CKD stage at baseline and at follow-up, converted into the following three categories: (1) recover (e.g., from Stage 3a \[at baseline\] to Stage 2 \[at follow-up\]); (2) stable (e.g., remaining Stage 3a at both baseline and follow-up); and (3) progress (e.g., from Stage 3a \[at baseline\] to Stage 3b \[at follow-up\]).

Change From Baseline in TTM Stage at 3 Months

Time Frame: Before initial intervention and 3 months after initial intervention

For each dyad, change from Baseline in TTM stage at 3 months was obtained by comparing the TTM stage of change at baseline and at follow-up, converted into the following three categories: (1) regress (e.g., from Preparation \[at baseline\] to Contemplation \[at follow-up\]); (2) maintain (e.g., remaining Action at both baseline and follow-up); and (3) advance (e.g., from Action \[at baseline\] to Maintanece \[at follow-up\]).

Change From Baseline in Health Promoting Lifestyle at 3 Months (Patient-specific)

Time Frame: Before initial intervention and 3 months after initial intervention

For each patient, change from Baseline (Followup score - Baseline score) in patient's Health Promoting Lifestyle at 3 months was assessed using the Chinese version of the Health Promoting Lifestyle Profile-II (HPLP-II), a validated scale with 52 items rated on a 4-point Likert scale. The total scores range from 52 to 208, with higher scores indicate better health-promoting behavior.

Change From Baseline in Quality of Life at 3 Months

Time Frame: Before initial intervention and 3 months after initial intervention

For each participant, change from Baseline (Followup score - Baseline score) in Quality of Life at 3 months was assessed using the first item of the Taiwanese version of the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF). The item was rated on a 5-point Likert scale, ranging from 1 to 5. Higher scores indicate better quality of life.

Secondary Outcomes

  • Change From Baseline in Adherence to Health Behaviors at 3 Months (Patient-specific)(Before initial intervention and 3 months after initial intervention)
  • Change From Baseline in Helping Relationships From Significant Others at 3 Months (Patient-specific)(Before initial intervention and 3 months after initial intervention)
  • Change From Baseline in Dyadic Adjustment at 3 Months(Before initial intervention and 3 months after initial intervention)

Study Sites (1)

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