A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD
Completed
- Conditions
- Attention Deficit Disorder With Hyperactivity
- Registration Number
- NCT02811211
- Lead Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
- Brief Summary
This noninterventional study will assess genomic changes in the metabotropic glutamate receptor (mGluR) network in children and adolescents with ADHD.
- Detailed Description
Male and female subjects 6 to 17 years of age with a primary psychiatric diagnosis of ADHD will be enrolled in this study. The subject and his or her parent/guardian must agree to genotyping to determine whether the subject has disruptive mutations within any of the approximately 274 mGluR-network genes, and complete an interview that will include information about the subject's ADHD history, treatment, and co-morbidities.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1894
Inclusion Criteria
- The subject is male or female ≥6 and ≤17 years of age.
- The subject has ADHD as defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition.
- The subject, his or her legally responsible representative, and investigator agree to complete ADHD history, treatment, and comorbidity electronic case report form (eCRF).
Exclusion Criteria
- The subject or parent/legal guardian is in the opinion of the investigator mentally or legally incapacitated and unable to provide informed consent/assent for participation in the study.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of mGluR network mutations At study enrollment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
A.I. DuPont Hospital for Children
🇺🇸Wilmington, Delaware, United States