Paclitaxel plus cisplatin and concurrent radiation for unresectable, locally recurrent or remnant gastric cancer in the left upper abdomen – phase I study
Phase 1
- Conditions
- unresectable, locally recurrent or remnant gastric cancer
- Registration Number
- JPRN-C000000246
- Lead Sponsor
- Multi-modality therapy for gastric cancer study group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
Not provided
Exclusion Criteria
1)Local tumor is not identified by computerized tomography (CT), endoscope or gastrointestinal examination 2)Other severe medical conditions 3)Patients need treatments for bowel obstruction or bleeding 4)Obvious infection or acute inflammatory condition 5)Allergy to drugs containing Cremophor EL (including cyclosporin) 6)Brain metastases with clinical symptom 7)Women who is pregnant, lactating or have the possibility of pregnancy 8)Patients who is judged inappropriate by lead principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Recommended dose
- Secondary Outcome Measures
Name Time Method 1)Dose-limiting toxicities 2)Maximum-tolerated dose 3)The improved rate of bowel stenosis 4)The improved rate of pain relief 5)Overall survival