Appropriateness of Antiepileptic Drug Use for Older Veterans
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9,682
- 试验地点
- 2
- 主要终点
- Type of Antiepileptic drug prescribed for individuals with new onset epilepsy
研究概览
简要总结
Nearly 2% of veterans >65 are actively treated for epilepsy, and the incidence is projected to increase with the aging of our society. Since commonly used antiepileptic drugs are considered suboptimal for older patients, it is important to understand existing patterns of treatment for older veterans with epilepsy.
详细描述
OBJECTIVE(S):
- Identify patient, provider, and system factors predicting adoption of recommended AEDs for treatment of newly diagnosed older veterans (FY00-04).
- Identify barriers to use of recommended AED in initial therapy for newly diagnosed older veterans with epilepsy.
- Assess and compare effectiveness of long-term use of various AED.
METHODS:
Using existing national VA outpatient, inpatient, and pharmacy databases in conjunction with Medicare inpatient and outpatient standard analytic files, the 1999 National Health Survey of VA Enrollees, American Hospital Association data, and primary data collection, we will identify the extent to which treatment for older veterans newly diagnosed with epilepsy changed between FY00-FY04, and identify predictors of change at the patient, provider, and system levels. We will begin to identify barriers to use of recommended AED using structured interviews with primary care and general neurology providers in sites with high and low use of suboptimal AEDs in incident cases. Finally, we will compare hospitalizations, emergency room visits, and fall-related injuries (including fractures) for patients on different AED regimens.
RESULTS:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 66 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Veterans 66 years and older receiving care from the Veterans Health Administration between fiscal years 2000-2004 Diagnosis of epilepsy and receiving anticonvulsant drugs
排除标准
- •No VA pharmacy data the year prior to epilepsy diagnosis
结局指标
主要结局
Type of Antiepileptic drug prescribed for individuals with new onset epilepsy
时间窗: Within one year of first epilepsy diagnosis
次要结局
未报告次要终点
