Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Phase 1

Withdrawn

• Conditions: Ischemic Stroke
• Interventions: Drug: warfarin; Drug: aspirin

• Registration Number: NCT00265408
• Lead Sponsor: University of California, San Diego

Brief Summary

Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.

Detailed Description

20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2005-12-12
• Study First Submitted QC: 2005-12-12
• Study First Posted: 2005-12-14
• Status Verified: 2007-03
• Study Completion: 2007-03
• Last Update Submitted: 2014-12-05
• Last Update Posted: 2014-12-08

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Clinical and imaging diagnosis of cervicocephalic arterial dissection within 3 months.

Exclusion Criteria

• Any contraindication to aspirin or warfarin.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
warfarin	warfarin	-
aspirin	aspirin	-

Primary Outcome Measures

Name	Time	Method
Incidence of stroke by one year.	1 year

Secondary Outcome Measures

Name	Time	Method
Recurrent dissection by one year.	1 year
Incidence of TIA by one year.	1 year
Incidence of major and minor bleeding episodes by one year.	1 year

Trial Locations

Locations (1)

UCSD Medical Center; 🇺🇸 San Diego, California, United States