Diagnostic Performance of a Rational and Standardized New Method for the Echocardiographic
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Anomaly
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
- Enrollment
- 4000
- Locations
- 1
- Primary Endpoint
- CAA
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and right. To overcome the echocardiographic limitations, the investigators designed, studied and implemented in our Institute a specific echocardiographic-based two-dimensional non-Doppler 4-views approach for the diagnosis of CAA.
Detailed Description
The method consisted of 4-CAA-focused specific views, routinely available from any echocardiographic exam: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views. PSAX, the traditional approach, along with the PLAX, and the apical 4/5-chambers views. A hallmark of CAA was considered the absence of a proper visualization of the origin of the coronary arteries from the aortic root. In addition, the presence of the ring sign, visualized from the PLAX was considered as abnormal. This sign is of interest when an aberrant left or right CAA is suspected. A coronary artery originating from the contralateral aortic sinus, along its intramural course, crosses the mid-anterior line of the circular aorta to reach the sinus of Valsalva of its intended origin. Consequently, its cross-section should be visible in an orthogonal view traversing the mid-long axis of the aorta, namely the parasternal long-axis view.
Investigators
Francesco Bianco
Researcher
ITAB - Institute for Advanced Biomedical Technologies
Eligibility Criteria
Inclusion Criteria
- •patients undergoing their first echocardiographic examination
Exclusion Criteria
- •already known congenital heart disease and cardiomyopathies
Outcomes
Primary Outcomes
CAA
Time Frame: At the time of the routine echocardiography assessment
The number of coronary arteries anomalies echocardiographically detected