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临床试验/NCT04224090
NCT04224090已完成不适用

Diagnostic Performance of a Rational and Standardized New Method for the Echocardiographic

ITAB - Institute for Advanced Biomedical Technologies1 个研究点 分布在 1 个国家目标入组 4,000 人开始时间: 2014年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
4,000
试验地点
1
主要终点
CAA

研究概览

简要总结

Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and right. To overcome the echocardiographic limitations, the investigators designed, studied and implemented in our Institute a specific echocardiographic-based two-dimensional non-Doppler 4-views approach for the diagnosis of CAA.

详细描述

The method consisted of 4-CAA-focused specific views, routinely available from any echocardiographic exam: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views. PSAX, the traditional approach, along with the PLAX, and the apical 4/5-chambers views.

A hallmark of CAA was considered the absence of a proper visualization of the origin of the coronary arteries from the aortic root. In addition, the presence of the ring sign, visualized from the PLAX was considered as abnormal. This sign is of interest when an aberrant left or right CAA is suspected. A coronary artery originating from the contralateral aortic sinus, along its intramural course, crosses the mid-anterior line of the circular aorta to reach the sinus of Valsalva of its intended origin. Consequently, its cross-section should be visible in an orthogonal view traversing the mid-long axis of the aorta, namely the parasternal long-axis view.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • patients undergoing their first echocardiographic examination

排除标准

  • already known congenital heart disease and cardiomyopathies

结局指标

主要结局

CAA

时间窗: At the time of the routine echocardiography assessment

The number of coronary arteries anomalies echocardiographically detected

次要结局

未报告次要终点

研究者

发起方
ITAB - Institute for Advanced Biomedical Technologies
申办方类型
Other
责任方
Principal Investigator
主要研究者

Francesco Bianco

Researcher

ITAB - Institute for Advanced Biomedical Technologies

研究点 (1)

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