Serial changes of echocardiography derived cardiac power output over the perioperative period in adult patients undergoing CABG: a prospective, observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- • Measurement of echocardiography derived cardiac power output (CPO) serially at different time-points of perioperative period and compare in between the time-points in patients undergoing coronary artery bypass grafting
研究概览
简要总结
This is a prospective, observational study. The primary objective of the study is to serially measure echocardiography derived cardiac power output during various time points in patients undergoing elective coronary artery bypass graft surgery. Patients are screened for inclusion criteria during preop evaluation and if they meet the criteria of inclusion and exclusion, they are explained about the study and its risk- benefits. Written informed consent is obtained. In the OT, echocardiography is used to obtain cardiac power output before and after induction of anaesthesia, before shifting the patient to ICU and on POD 7. A total of 54 patients are considered to be taken up for the study and conclusion will be drawn after statistical analysis.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients of either gender and between 20 and 60 years of age undergoing more than or equal to two grafts coronary artery bypass grafting surgery.
排除标准
- •Declined consent
- •Concomitant moderate/severe valvular heart disease
- •Patients not with sinus rhythm at the time of performing TEE/TTE.
- •Patients on Pacemaker.
- •Contraindications to transesophageal echocardiography
- •Patients with poor TTE window
- •Re-operative/emergency surgery
- •Significant non-cardiac organ disease
- •Inotropic/mechanical support prior to induction of anaesthesia.
结局指标
主要结局
• Measurement of echocardiography derived cardiac power output (CPO) serially at different time-points of perioperative period and compare in between the time-points in patients undergoing coronary artery bypass grafting
时间窗: Before induction of anaesthesia and after induction of anaesthesia; immediately after surgery and postoperative day 7
次要结局
- • Measurement of echocardiography derived cardiac power index (CPI) and stroke output serially at different time-points of perioperative period and compare in between the time-points (Before induction of anaesthesia and after induction of anaesthesia; immediately after surgery and postoperative day 7) in patients undergoing coronary artery bypass grafting(• To assess relation between the changes in CPO, CPI and stroke output values from before induction to after induction of anaesthesia time points and that from immediately after surgery to postoperative day 7 time points with the age, EuroScore, pre-induction ejection fraction (LVEF) and pre-induction peak LV global longitudinal strain of the patients undergoing coronary artery bypass grafting)
研究者
Sahithya K
PGIMER, Chandigarh