Prediction of Clinical Efficacy of Acupuncture Treatment for Migraine Based on Machine Learning Algorithms: A DTI Study

Phase 1

• Conditions: Migraine

• Registration Number: ITMCTR2100005202
• Lead Sponsor: Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1)Comply with the diagnostic criteria of the International Classification of Headache Disorders III (ICHD-3 beta);
2)18-65 years old, right handedness;
3)A history of migraine for at least 1 year;
4)The frequency of migraine attack more than twice a month;
5)No acupuncture treatment or medication was used within 24 hours after the acute onset of migraine, and no preventive treatment for migraine during the past 3 months;
6)Sign written informed consent.

Exclusion Criteria

1)Other types of primary headaches such as chronic migraine, tension-type headaches, nerve headache and cluster headache;
2)Any other secondary headaches or neurological diseases-headaches caused by intracranial diseases such as otolaryngological diseases, depression and Parkinson's disease;
3)Relatively severe life-threatening diseases, such as cardiovascular diseases, acute infectious diseases, hematological diseases, endocrine diseases, allergies or hemoptysis;
4)Use of prophylactic migraine medication and acupuncture treatment during the past three months.
5)Pregnancy, lactation and preparation for pregnancy;
6)Smoking, alcohol and drug abuse;
7)Patients with pain within 3 days before MR scan;
8)Any contraindications of acupuncture treatment, such as hematological diseases and local infections, etc;
9)Any contraindications for MRI exam, such as metal implants in the body, claustrophobia, etc.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Halving rate of headache days;

Secondary Outcome Measures

Name	Time	Method
Migraine disability assessment;Beck depression inventory;Visual analogue scale;Self-rating anxiety scale;Headache impact test-6;