Study of the Functioning of Prospective Memory in Breast Cancer and the Influence of Sleep
Overview
- Phase
- Not Applicable
- Intervention
- Neuropsychological, psycho-pathological and quality of life assessments
- Conditions
- Breast Cancer
- Sponsor
- Centre Francois Baclesse
- Enrollment
- 75
- Locations
- 2
- Primary Endpoint
- The memory components and memory loss mechanisms by questionnaires
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The results of this study will contribute to a better understanding of prospective memory deficit processes in breast cancer in relation to sleep disorders frequently reported in this pathology. In the long term, a better understanding will make it possible to envisage appropriate treatments to compensate for these memory difficulties and to improve the autonomy of the patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Major patients under the age of 70;
- •Patients who have been treated by surgery or radiotherapy for non-metastatic breast cancer
- •Radiotherapy completed for about 6 months
- •Level of study 3 "end of primary studies" minimum (Barbizet scale);
- •French mother tongue;
- •Menopausal women for at least 1 year before the selection visit
- •Absence of primary cancer of the central nervous system or brain metastases;
- •Absence of previous neurological damage;
- •Absence of personality disorders and progressive psychiatric pathology;
- •Having signed the informed consent to participate in the study.
Exclusion Criteria
- •Primary cancer other than breast
- •Metastatic cancer
- •Treated by chemotherapy
- •Cognitive function disorders pre-existing to cancer diagnosis
- •Patients with paraneoplastic syndrome;
- •Evolutionary psychiatric pathology;
- •Refusal of participation;
- •Patients unable to respond to cognitive tests;
- •Drug use or excessive consumption of alcohol.
Arms & Interventions
Group A
Patients perform neuropsychological, psycho-pathological and quality of life assessments, and sleep tests
Intervention: Neuropsychological, psycho-pathological and quality of life assessments
Group A
Patients perform neuropsychological, psycho-pathological and quality of life assessments, and sleep tests
Intervention: Hormonotherapy
Group B
Patients perform neuropsychological, psycho-pathological and quality of life assessments, and sleep tests
Intervention: Neuropsychological, psycho-pathological and quality of life assessments
Healthy volunteers
Healthy volunteers perform neuropsychological, psycho-pathological and quality of life assessments, and sleep tests
Intervention: Neuropsychological, psycho-pathological and quality of life assessments
Outcomes
Primary Outcomes
The memory components and memory loss mechanisms by questionnaires
Time Frame: 6 months after the end of radiotherapy
Secondary Outcomes
- The impact of adjuvant hormone therapy on the functioning of prospective memory by questionnaires(6 months after the end of radiotherapy)
- The influence of anxio-depressive factors and fatigue on prospective memory by questionnaires(6 months after the end of radiotherapy)
- The effect of sleep quality on the recovery of intentions in prospective memory by questionnaires(6 months after the end of radiotherapy)